Oxycodone and Percocet are both prescription medications used to manage moderate to severe pain, but they differ in composition and strength. Oxycodone is an opioid painkiller available alone, while Percocet combines oxycodone with acetaminophen, which enhances pain relief. Percocet may provide stronger analgesic effects for some patients but carries the additional risk of acetaminophen-related liver damage if overused. Both drugs carry risks of dependence, misuse, and side effects like drowsiness or nausea. Choosing the right medication depends on pain severity, medical history, and professional guidance. Safe use under a doctor’s supervision is essential to minimize risks and maximize effectiveness.